Hauj lwm lawm

Kev tsis

Ruxolitinib feem ntau yog siv rau kev kho mob ntawm qee yam kab mob hematological, tshwj xeeb tshaj yog myelofibrosis thiab polycythemia vera, uas yog hom qog nqaij hlav ntshav hu ua myeloproliferative neoplasms. Nws kuj tseem tuaj yeem siv los kho steroid-refractory acute graft-piv txwv-tus kab mob (GVHD) hauv cov neeg mob uas tau hla hematopoietic qia cell transplantation.

Ruxolitinib yog ib qho kev xaiv Janus kinase (JAK) inhibitor. Nws yog ib qho tshuaj me me uas ua los ntawm inhibiting cov enzymes tshwj xeeb hu ua JAK1 thiab JAK2.

Ruxolitinib CAS 941678-49-5

Khoom: Ruxolitinib CAS 941678-49-5
Lwm Lub Npe: INCB018424; Ruxolitinib; Ruxolitinib Phosphate API; Ruxolitinib API; Ruxolitinib Intermediates;
Lub npe tshuaj: (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1 H-pyrazol{11}}yl]propanenitrile
Cov mis mos molecular: 306.37
Molecular mass: C₁₇H₁₈N₆
CAS Nr.: 941678-49-5
MDL Nr.: MFCD12031592
Ruxolitinib Intermediates: CAS 1029716-44-6; CAS 591769-05-0; CAS 1236033-05-8

Ruxolitinib, nrog CAS tus lej 941678-49-5, yog cov tshuaj uas feem ntau siv los kho qee yam ntshav tsis txaus thiab mob o. Nov yog qee qhov kev siv ntawm Ruxolitinib:

1. Myelofibrosis: Ruxolitinib tau pom zoo rau kev kho mob myelofibrosis, ib qho tsis tshua muaj pob txha pob txha tsis zoo uas tshwm sim los ntawm kev tsim cov qe ntshav tsis zoo thiab kev loj hlob ntawm cov ntaub so ntswg fibrous hauv cov pob txha. Nws pab txo cov tsos mob xws li mob poov xab, qaug zog, thiab tawm hws hmo ntuj, thiab tuaj yeem txhim kho tag nrho lub neej zoo rau cov neeg mob myelofibrosis.

2. Polycythemia Vera: Ruxolitinib kuj tseem siv rau hauv kev kho mob ntawm polycythemia vera, mob qog noj ntshav ntev uas tshwm sim los ntawm kev tsim cov qe ntshav liab ntau dhau. Nws pab tswj tus kab mob los ntawm kev txo qhov xav tau ntawm phlebotomy (bloodletting) thiab tswj cov tsos mob cuam tshuam nrog tus po loj.

3. Graft-versus-Host Disease (GVHD): Qee zaum Ruxolitinib yog siv los kho cov kab mob graft-versus-host, ib qho teeb meem uas tuaj yeem tshwm sim tom qab hloov qia cell. Nws pab txo qhov mob thiab cov tsos mob cuam tshuam nrog GVHD, xws li daim tawv nqaij ua pob khaus, teeb meem plab hnyuv, thiab teeb meem daim siab.

4. Rheumatoid Arthritis: Ruxolitinib tau pom muaj peev xwm hauv kev kho mob rheumatoid mob caj dab, kab mob autoimmune uas ua rau mob pob qij txha thiab kev puas tsuaj. Nws raug soj ntsuam raws li kev xaiv kho mob rau cov neeg mob uas tsis tau teb zoo rau lwm cov tshuaj.

5. Alopecia Areata: Ruxolitinib kuj tau qhia cov lus cog tseg hauv kev kho mob ntawm alopecia areata, ib qho mob autoimmune uas ua rau cov plaub hau poob. Nws yog feem ntau siv topically raws li ib tug cream los yog gel formulation los txhawb cov plaub hau regrowth nyob rau hauv cov cheeb tsam cuam tshuam.

1. Lub sijhawm them nyiaj

TT, LC

2. Hnub xa khoom

Sib tham tau

3. Kev ua lag luam

Middle East / Africa / Asia / South America / Europe

4. Qauv

Muaj

5. Cov qauv kev tswj hwm
EP/USP/JP

6. Daim ntawv pov thawj tsim nyog

Kev tso npe "A" raws li txoj cai ntawm cov khoom ntim khoom raw, Kev Ceeb Toom Kev Pom Zoo ntawm kev lag luam

7. Ntim me me specification

Pem hauv ntej pob: ib txheej polyethylene hnab thiab txhuas ntawv ci hnab.

Sab nrauv pob: fiber nruas.

Ntim loj: 25 kg / nruas; 1 kg / nruas; 5kg / nruas.

Peb Qhov Zoo

Peb muaj cov chaw ua haujlwm hauv Dubai thiab Is Nrias teb

peb muaj tus kheej txhim khu kev qha & Kev koom tes ntev & kev paub txog lub Hoobkas

Ntau yam khoom rau xaiv los ntawm Tuam Tshoj thiab Is Nrias teb

Peb tuaj yeem kho raws li koj xav tau

Peb tuaj yeem ua OEM & ODM

Peb tuaj yeem muab N-1 rau API

Ruxolitinib CAS 941678-49-5 API FAQ

Q: Cov tshuaj ruxolitinib siv rau dab tsi?

A: Ruxolitinib yog cov tshuaj siv los tswj thiab kho myelofibrosis, polycythemia vera, thiab steroid-refractory acute graft-tiv thaiv-tus kab mob. Nws yog nyob rau hauv Janus Kinase inhibitor chav kawm ntawm cov tshuaj.

Q: Tus lej CAS rau ruxolitinib 941678-49-5 yog dab tsi?

A: 941678-49-5

Q: ruxolitinib CAS 941678-49-5 FDA pom zoo yog dab tsi?

A: FDA pom zoo keeb kwm.Nws tau qhia txog kev kho mob ntawm: nruab nrab lossis muaj kev pheej hmoo siab myelofibrosis, suav nrog thawj myelofibrosis, post-polycythemia vera myelofibrosis thiab post-tseem ceeb thrombocythemia myelofibrosis hauv cov laus.

Q: Puas yog ruxolitinib CAS 941678-49-5 txhim kho txoj sia?

A: Kev kho Ruxolitinib tuaj yeem ua rau txo qis hauv hemoglobin hauv qee cov neeg mob MF; Txawm li cas los xij, cov qib feem ntau ruaj khov hauv 24 txog 36 lub lis piam. Tsis tas li ntawd, ib tsab ntawv tshaj tawm yav dhau los qhia tau hais tias ruxolitinib tau cuam tshuam nrog kev muaj sia nyob ntev tsis hais txog cov xwm txheej hauv paus hauv paus.

Q: Vim li cas ruxolitinib CAS 941678-49-5 ua rau hnyav nce?

A: Ruxolitinib tuaj yeem ua rau qhov hnyav nce los ntawm kev thaiv leptin signaling hauv hlwb ntawm JAK2 / STAT3. Ntshav.

Q: Cov zaub mov dab tsi yuav tsum zam thaum noj ruxolitinib CAS 941678-49-5?

A: Tsis txhob noj txiv kab ntxwv lossis haus cov kua txiv kab ntxwv thaum siv cov tshuaj no tshwj tsis yog koj tus kws kho mob lossis tus kws muag tshuaj hais tias koj yuav ua li ntawd yam xyuam xim. Grapefruit tuaj yeem ua rau muaj feem cuam tshuam nrog cov tshuaj no.

Q: Ruxolitinib CAS 941678-49-5 tswj hwm li cas?

A: Ruxolitinib muaj nyob rau hauv cov ntsiav tshuaj ntawm qhov ncauj thiab feem ntau yog noj los ntawm qhov ncauj.

Q: Cov mob lossis kab mob dab tsi uas Ruxolitinib CAS 941678-49-5 kho?

A: Ruxolitinib feem ntau yog siv rau kev kho mob myelofibrosis, ib hom kab mob hauv cov pob txha, thiab polycythemia vera, ntshav qog ntshav. Nws kuj tseem tuaj yeem siv los kho steroid-refractory acute graft-piv txwv-tus kab mob (GVHD) hauv cov neeg mob uas tau hla hematopoietic qia cell transplantation.

Q: Ruxolitinib CAS 941678-49-5 ua haujlwm li cas?

A: Ruxolitinib yog ib qho kev xaiv Janus kinase (JAK) inhibitor. Nws ua haujlwm los ntawm kev thaiv kev ua haujlwm ntawm cov enzymes hu ua JAK1 thiab JAK2, uas koom nrog hauv cov xov tooj ntawm tes taw qhia txoj hauv kev cuam tshuam txog kev tiv thaiv kab mob thiab kev tsim cov ntshav. Los ntawm inhibiting cov enzymes, Ruxolitinib pab tswj kev loj hlob ntawm tes tsis zoo thiab txo qhov mob ntawm qee yam kab mob.

Cim npe nrov: ruxolitinib cas 941678-49-5, Tuam Tshoj ruxolitinib cas 941678-49-5 manufacturers, lwm tus neeg, Hoobkas