Vonoprazan fumarate yog ntsev daim ntawv ntawm vonoprasan, uas yog lub active tshuaj muaj. Nws yog feem ntau siv rau kev kho mob ntawm cov kab mob hauv plab, xws li kab mob gastroesophageal reflux (GERD), gastric ulcers, thiab duodenal ulcers.
Vonoprazan ua haujlwm los ntawm kev xaiv thiab thim rov qab inhibiting H + / K+-ATPase enzyme, feem ntau hu ua lub twj tso kua mis proton, hauv plab parietal hlwb. Qhov no inhibition txo qhov zus tau tej cov gastric acid, uas ua rau kom muaj kev tiv thaiv ntawm acid secretion.
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Yam khoom |
Txuj kev cai |
Kev Xeem |
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Qhov tshwm sim |
Qhov tshwm sim |
Dawb mus rau dawb dawb crystalline hmoov los yog crystalline hmoov |
Off-dawb crystalline hmoov |
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Kev tsom xam |
Fluorine check |
3.9%-4.3% |
4.2% |
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Chlorides |
Tsis ntau tshaj 0.05% |
Ua raws |
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Ammonium ntsev |
Tsis ntau tshaj 0.05% |
Ua raws |
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Sulfate |
Tsis ntau tshaj 0.05% |
Ua raws |
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Dej |
Tsis ntau tshaj 0.40% |
Ua raws |
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Residue ntawm Ignition |
Tsis ntau tshaj 0.10% |
0.021% |
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Cov hlau hnyav |
Tsis ntau tshaj 20 ppm |
Ua raws |
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Organic impurities |
Ib qho impurity: tsis ntau tshaj 0.15% |
0.062% |
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Tag nrho impurity: tsis ntau tshaj 1.0% |
0.25% |
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Residual Solvents |
Methanol: tsis ntau tshaj 0.30% |
Tsis pom |
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Ethanol: tsis ntau tshaj 0.50% |
Tsis pom |
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Ethyl acetate: tsis ntau tshaj 0.50% |
Tsis pom |
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Dichloromethane: tsis ntau tshaj 0.060% |
Tsis pom |
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Acetonitrile: tsis ntau tshaj 0.041% |
Tsis pom |
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Tetrahydrofuran: tsis ntau tshaj 0.072% |
Tsis pom |
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Benzene: tsis moare tshaj 0.020% |
Tsis pom |
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Pyridine: tsis ntau tshaj 0.020% |
Tsis pom |
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N, N-Dimethylacetamide: tsis ntau tshaj 0.10% |
Tsis pom |
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Methylamine: tsis ntau tshaj 0.10% |
Tsis pom |
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Acetic acid: tsis ntau tshaj 0.50% |
Tsis pom |
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Cov ntsiab lus ntawm Fumaric acid |
23.9%-26.4% |
24.5% |
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Assay |
NLT 98.0% thiab NMT 102.0% ntawm C17H16FN3O2S.C4H4O4, xam nyob rau hauv lub hauv paus anhydrous |
99.2% |
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Vonoprazan Fumarate TAK-438 1260141-27-2

Khoom: Vonoprazan Fumarate TAK-438
Lwm lub npe: TAK438; TXAUS -438
CAS Nr.: 1260141-27-2
Daim ntawv thov: Nws zoo tshem tawm cov kua qaub ntawm gastric acid, yog li ua tiav cov kua qaub
Khoom Qeb: Gastrointestinal API, Pepsin digestive enzyme API, Pancreatin digestive enzyme API
Molecular Formula: C21H20FN3O6S
MDL Nr.: MFCD18633280
1. Lub sijhawm them nyiaj
TT, LC
2. Hnub xa khoom
Sib tham tau
3. Kev ua lag luam
Middle East / Africa / Asia / South America / Europe
4. Qauv
Muaj
5. Cov qauv kev tswj hwm
PIB, EP, IP
6. Daim ntawv pov thawj
Kev tso npe "A" raws li txoj cai ntawm cov khoom ntim ntim, Kev Ceeb Toom Kev Pom Zoo ntawm kev lag luam daim ntawv thov rau chemical API, WC, COPP, CEP, EUGMP, US DMF tus lej sau npe, Is Nrias teb daim ntawv pov thawj, npe Brazil, npe Malaysia, thiab lwm yam.
7. Packing size specification
Pem hauv ntej pob: ib txheej polyethylene hnab thiab txhuas ntawv ci hnab.
Sab nrauv pob: fiber nruas.
Ntim loj: 20 kg / nruas; 1 kg / nruas; 5kg / nruas.
Peb Qhov Zoo
Peb muaj cov chaw ua haujlwm hauv Dubai thiab Is Nrias teb
peb muaj tus kheej txhim khu kev qha & Kev koom tes ntev & kev paub txog lub Hoobkas
Ntau yam khoom rau xaiv los ntawm Tuam Tshoj thiab Is Nrias teb
Peb tuaj yeem kho raws li koj xav tau
Peb tuaj yeem ua OEM & ODM
Peb tuaj yeem muab N-1 rau API
Vonoprazan Fumarate 1260141-27-2 FAQ
Q: Yuav ua li cas yog Vonoprasan Fumarate API tswj?
Q: Puas muaj cov kev mob tshwm sim ntawm Vonoprasan Fumarate API?
Q: Puas tuaj yeem siv Vonoprasan Fumarate API hauv qee cov neeg mob?
Q: Puas tuaj yeem siv Vonoprasan Fumarate API thaum cev xeeb tub lossis thaum pub niam mis?
Cev xeeb tub: Muaj cov ntaub ntawv txwv tsis pub muaj nyob ntawm kev nyab xeeb ntawm Vonoprasan Fumarate API thaum cev xeeb tub. Cov kev tshawb fawb tsiaj tau pom tias muaj kev pheej hmoo rau tus menyuam hauv plab, tab sis tsis muaj kev tshawb fawb txaus thiab tswj tau zoo hauv cov poj niam cev xeeb tub. Kev siv cov tshuaj no thaum cev xeeb tub yuav tsum tau ua tib zoo soj ntsuam, ntsuas cov txiaj ntsig zoo tiv thaiv kev pheej hmoo rau tus menyuam hauv plab.
Kev pub niam mis: Nws tsis paub tias yog Vonoprasan Fumarate API raug tso tawm hauv tib neeg cov kua mis. Cov kev tshawb fawb hauv cov tsiaj tau pom tias excretion ntawm cov tshuaj thiab nws cov metabolites hauv cov mis nyuj. Vim tias muaj feem cuam tshuam rau tus menyuam mos, yuav tsum txiav txim siab seb yuav tsum tsis txhob pub mis niam lossis txiav cov tshuaj, suav nrog qhov tseem ceeb ntawm cov tshuaj rau leej niam.
Cim npe nrov: Vonoprazan fumarate cas 1260141-27-2, Tuam Tshoj vonoprasan fumarate cas 1260141-27-2 tuam ntxhab, lwm tus neeg, Hoobkas







