Hauj lwm lawm

Kev tsis

Vim li cas thiaj xaiv peb?

Kev daws teeb meem ib zaug

Kev paub nplua nuj

Fengfu Pharma, headquartered nyob rau hauv Hangzhou, Tuam Tshoj, nrog 3 ntau lawm bases nyob rau hauv Shandong, Zhejiang thiab Hebei nyias, uas muaj ntau xyoo ntawm kev paub nyob rau hauv zus tau tej cov APIs, vitamins thiab tshuaj cov khoom. Cov chaw no tau lees paub GMP, ISO, FAMI-QS, KOSHER, HALAL, thiab lwm yam.

Siab zoo

Peb tau ua tiav kev tswj hwm peb cov khoom tsim, tsim, thiab tsim cov txheej txheem, ua tsaug rau peb cov cuab yeej siv siab heev, cov txheej txheem, thiab cov chaw soj ntsuam.

Kev pabcuam zoo

Peb lub hom phiaj yog los muab koj cov khoom lag luam zoo thiab cov kev pabcuam tshaj lij rau kev sib nrig sib pab. Peb kuj txaus siab ua haujlwm nrog cov neeg koom tes thoob ntiaj teb los tsim kom muaj lub neej yav tom ntej zoo ua ke.

Ruxolitinib CAS yog dab tsi 941678-49-5

Ruxolitinib yog siv los kho myelofibrosis nruab nrab lossis muaj kev pheej hmoo siab, suav nrog thawj myelofibrosis, post-polycythemia vera myelofibrosis thiab post-tseem ceeb thrombocythemia myelofibrosis. Myelofibrosis yog ib qho teeb meem ntawm pob txha caj qaum uas ua rau lub neej muaj teeb meem uas tshwm sim los ntawm cov tsos mob hauv qab no: tus kab mob loj (splenomegaly), khaus khaus, ua npaws, hmo ntuj tawm hws, poob phaus, mob pob txha, lossis qaug zog lossis qaug zog. Nws kuj tseem siv los kho polycythemia vera hauv cov neeg mob uas tau kho yav dhau los nrog hydroxyurea uas tsis ua haujlwm zoo.
Ruxolitinib kuj tseem siv los kho cov kab mob graft-tiv thaiv tus tswv tsev (aGVHD) hauv cov neeg mob uas tau kho nrog lwm cov tshuaj (xws li steroids) uas tsis ua haujlwm zoo. Nws kuj tseem siv los kho tus kab mob chronic graft-vsus-host disease (cGVHD) hauv cov neeg mob uas tau kho nrog 1 lossis 2 cov kev kho mob yav dhau los uas tsis ua haujlwm zoo.

Polymyxin B Sulfate CAS TSIS TAU

Khoom: Polymyxin B Sulfate CAS 1405-20-5
Lub npe tshuaj: Polymyxin B, sulfate (ntsev); Polymyxin B; Polymyxin-B-Sulfat; Sulfato De Polimixina B; Polymyxin B (PMB); PMB; Polymyxin B sulfate USP; Polymyxin B Sulfate 1405-20-5; Einecs 215-774-7;
CAS Nr.: 1405-20-5

Parecoxib sodium CAS

Khoom: Parecoxib Sodium CAS 198470-85-8
Lwm Lub Npe: Parecoxib Sodium; Parecoxib; Parecoxib Sodium API; Parecoxib Sodium API;
Lub npe tshuaj: 4-(5-methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide sodium ntsev
Cov mis mos molecular: C19H18N2O4S·Na
Molecular hnyav: 392.409

Vonoprazan Fumarate CAS 1260141-27-2

Khoom: Vonoprazan Fumarate TAK-438
Lwm lub npe: TAK438; TXAUS -438
CAS Nr.: 1260141-27-2
Daim ntawv thov: Nws zoo tshem tawm cov kua qaub ntawm gastric acid, yog li ua tiav cov kua qaub
Khoom Qeb: Gastrointestinal API, Pepsin digestive enzyme API, Pancreatin digestive enzyme API

Fusidic Acid CAS 6990-06-3

Khoom: Fusidic Acid 6990-06-3
Lub npe tshuaj: Fusidic acid; Fusidic Acid API; Fusidic Acid Active Pharmaceutical Ingredient; CAS 6990-06-3; Acide Fusidique; Acido Fusidico; 6990-06-3;
CAS Nr.: 6990-06-3
Cov yam ntxwv ntawm lub cev: hmoov dawb
Cov mis mos molecular: C31H48O6 · 1/2 H2O

Vonoprazan Fumarate CAS 881681-01-2

Khoom: Vonoprazan Fumarate CAS 881681-01-2
Lub npe tshuaj: 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl )-N-methylmethanamine fumarate
Lwm lub npe: TAK438; TAK-438; MFCD18633280; 1260141-27-2 TAK-438 AKSci J97352; Fumarat Vonoprazana; Vonoprasan Fumarate-D3; N-methyl-1-(3-pyridyl sulfonyl)-1H-pyrrole-3-methanamine; 1-(5-(2-Fluorophenyl); AB457904 CAS 881681-01-2;

Sodium Fusidate CAS TSIS TAU: 751-94-0

Khoom: Sodium Fusidate CAS 751-94-0
Lub npe tshuaj: Fusidate De Sodium; Fusidato De Sodio; Fuzydyt Alsudium; Natriy Fuzidat; 751-94-0; Fucidina; Fucidine; Fusidatesodium; Fusidin; Fusin; Intertullefucidin; Sodium fusidate siv tshuaj;
CAS Nr.: 751-94-0
Cov yam ntxwv ntawm lub cev: Cov hmoov dawb crystalline, thiab cov kuab tshuaj yog cov kua ntshiab tsis muaj xim.

Bacitracin Zinc CAS 1405-89-6

Khoom: Bacitracin Zinc CAS 1405-89-6
Lwm Lub Npe: Bacitracina De Zinc; Batsitrazin Tsink; Bacitracina De Zinco; CAS 1405-89-6; 1405-89-6;
Cov yam ntxwv ntawm lub cev: daj ntseg daj mus rau xim av-daj hmoov; odorless nrog ib tug iab saj.
Cov mis mos molecular: C66H103N17O16SZn

Lincomycin HCL CAS Nr.

Khoom: Lincomycin HCL CAS 859-18-7
Lwm Lub Npe: Lincomycin Hcl; lincomycin hydrochloride; methyl 6,8-dideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-D-erythro-alpha -D-galacto-octopyranoside hydrochloride; Lincomycin hydrochloride anhydrous; CAS 859-18-7; 859-18-7; Hidrocloruro De Lincomicina; Hidruklurid Alllinkomaisin; Lincocin; Lincomix; Lincomycin Monohydrochloride;

Pazufloxacin Mesilate CAS TSIS TAU

Khoom: Pazufloxacin Mesylate CAS 163680-77-1
Lwm Lub Npe: Pazufloxacin Methanesulfonate; pazufloxacin mesylate; Pazufloxacin MS; Pazufloxacin MSLT; Pazufloxacin Methanesulphonate; 163680-77-1; Pazufloxacin mesilate; Pazucross; Pazufloxacin (mesylate); Pazufloxaxin methanesulfonate; Pasil; T-3762;

Ruxolitinib CAS 941678-49-5 Ua haujlwm li cas

Ruxolitinib yog ib hom tshuaj tiv thaiv kab mob qog noj ntshav hu ua mob cancer loj hlob blocker. Tus kab mob qog noj ntshav thaiv kev loj hlob los thaiv cov yam tseem ceeb ntawm kev loj hlob Qhib cov ntsiab lus uas ua rau cov qog nqaij hlav qog noj ntshav sib faib thiab loj hlob. Ruxolitinib ua haujlwm los ntawm kev thaiv cov noob Qhib cov ntsiab lus uas yog qhov tseem ceeb hauv kev tsim cov qe ntshav Qhib cov lus piav qhia. Cov noob no hu ua Janus Associated Kinases 1 lossis 2 (JAK 1 lossis JAK2).
Koj muaj kev kuaj ntshav los kuaj JAK gene hloov ua ntej koj pib kho.

Yuav ua li cas Ruxolitinib CAS 941678-49-5 Muab

Koj yuav tau muab ruxolitinib ua cov ntsiav tshuaj uas koj noj tom tsev.
Thaum kho, koj feem ntau pom ib qho:
● Tus kws kho mob qog ntshav ntshav (hematologist)
● Tus kws saib xyuas mob qog noj ntshav lossis kws kho mob tshwj xeeb
● Tus kws muag tshuaj tshwj xeeb.
Koj yuav tau kuaj ntshav tas li thaum koj kho. Cov no tso cai rau koj tus kws kho mob kuaj:
● Cov qe ntshav sib txawv (cov ntshav suav) hauv koj lub cev
● Koj lub siab thiab lub raum ua haujlwm li cas
● Kev kho mob zoo npaum li cas.
● Koj txoj kev kho mob
Tus nais maum lossis tus kws muag tshuaj yuav muab cov tshuaj ruxolitinib rau koj coj mus tsev. Ib txwm coj lawv raws nraim li tau piav qhia. Qhov no yog qhov tseem ceeb kom paub tseeb tias lawv ua haujlwm zoo li qhov ua tau rau koj.
Koj tus nais maum lossis tus kws muag tshuaj kuj tseem yuav muab lwm yam tshuaj rau koj coj mus tsev. Noj tag nrho koj cov tshuaj thiab tshuaj raws nraim li lawv tau piav qhia rau koj.
Koj tus kws kho mob yuav tsum tau hloov cov koob tshuaj ruxolitinib thoob plaws koj txoj kev kho mob. Qhov no nyob ntawm seb koj qhov kev kuaj ntshav li cas.
Koj feem ntau yuav txuas ntxiv noj ruxolitinib ntev npaum li nws ua haujlwm zoo rau koj thiab txhua yam kev mob tshwm sim tuaj yeem tswj tau. Nws yog ib qho tseem ceeb uas koj tsis txhob noj nws yam tsis tau tham nrog koj tus kws kho mob ua ntej. Tso tseg cov tshuaj tam sim ntawd yuav ua rau koj tsis xis nyob. Cov kws kho mob feem ntau txo koj cov koob tshuaj ua ntej tso tseg tag.
● Noj ruxolitinib ntsiav tshuaj
Feem ntau koj noj ruxolitinib ntsiav tshuaj 2 zaug hauv ib hnub. Coj lawv tib lub sijhawm txhua hnub. Noj cov ntsiav tshuaj nrog lossis tsis muaj zaub mov. Noj cov ntsiav tshuaj tag nrho nrog ib khob dej. Tham nrog koj tus kws kho mob lossis kws muag tshuaj yog tias koj pom qhov nyuaj no. Tsis txhob zom, qhib lossis tsoo koj cov ntsiav tshuaj.
Yog tias koj tsis nco qab noj koj cov ruxolitinib, tsis txhob noj ob zaug. Ua raws li koj lub sijhawm teem tseg thiab noj koj cov koob tshuaj ntxiv rau lub sijhawm.
Lwm yam uas yuav tsum nco ntsoov txog koj cov ntsiav tshuaj:
● Khaws cov ntsiav tshuaj rau hauv lawv cov pob thawj, ntawm chav tsev kub, thiab kom deb ntawm tshav kub thiab tshav ntuj ncaj qha.
● Khaws cov ntsiav tshuaj kom tsis txhob pom thiab ncav cuag cov menyuam yaus.
● Yog tias koj mob tom qab noj cov ntsiav tshuaj, hu rau tsev kho mob. Tsis txhob noj lwm koob.
● Yog tias koj qhov kev kho mob raug tso tseg rov qab cov ntsiav tshuaj uas tsis tau siv rau tus kws muag tshuaj.

Cov lus qhia tshwj xeeb rau Ruxolitinib CAS 941678-49-5

● Vim hais tias ruxolitinib tuaj yeem ua rau yug me nyuam, tsis txhob noj cov tshuaj no yog tias koj cev xeeb tub. Cov txiv neej thiab cov poj niam uas noj ruxolitinib yuav tsum siv txoj kev tiv thaiv kev yug menyuam.
● Tsis paub tias ruxolitinib nkag mus rau hauv cov kua mis. Cov tshuaj no yuav ua rau mob hnyav rau tus me nyuam mos. Cov poj niam uas noj ruxolitinib yuav tsum tsis txhob pub niam mis.
● Ruxolitinib ntsiav tshuaj yuav tsum tau muab cia rau hauv chav tsev kub.
● Khaws cov tshuaj no thiab txhua yam tshuaj kom deb ntawm menyuam yaus thiab tsiaj.
● Lwm yam tshuaj yuav cuam tshuam rau txoj kev ruxolitinib ua haujlwm. Ib txwm muab ib daim ntawv teev cov tshuaj uas koj noj rau koj tus kws kho mob lossis tus kws muag tshuaj. Tshawb xyuas nrog koj tus kws kho mob lossis tus kws muag tshuaj ua ntej noj cov vitamins tshiab, tshuaj ntsuab, lossis lwm yam tshuaj.
● Tsis txhob haus cawv txiv hmab thiab kua txiv hmab txiv ntoo thaum noj ruxolitinib.
● Yog tias koj tsis noj tshuaj, ua raws li cov lus qhia no:
1. Rov qab mus rau lub sijhawm noj tshuaj ib txwm muaj.
2. Tsis txhob muab lwm koob.

Yuav Siv Li Cas Ruxolitinib CAS 941678-49-5

Ruxolitinib los ua ib ntsiav tshuaj noj los ntawm qhov ncauj. Nws feem ntau yog noj nrog lossis tsis muaj zaub mov ob zaug hauv ib hnub. Noj ruxolitinib ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj kom zoo, thiab nug koj tus kws kho mob lossis tus kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj ruxolitinib raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua, lossis noj ntau dua li koj tus kws kho mob tau sau tseg.
Yog tias koj tau txais kev kho mob myelofibrosis lossis PV koj tus kws kho mob yuav pib txhaj tshuaj ruxolitinib qis rau thawj plaub lub lis piam ntawm kev kho mob, thiab maj mam nce koj cov koob tshuaj tom qab lub sijhawm ntawd, tsis pub ntau tshaj ib zaug txhua 2 lub lis piam. Yog tias koj tau txais kev kho mob rau tus mob GVHD, koj tus kws kho mob yuav pib koj ntawm koob tshuaj ruxolitinib qis thiab tuaj yeem nce koj cov koob tshuaj tom qab tsawg kawg 3 hnub ntawm kev kho. Yog tias koj tau txais kev kho mob hnyav lossis mob GVHD koj tus kws kho mob yuav maj mam txo koj cov koob tshuaj ruxolitinib tom qab tsawg kawg 6 lub hlis ntawm kev kho.
Yog tias koj tsis tuaj yeem noj zaub mov ntawm qhov ncauj thiab muaj lub raj nasogastric (NG), koj tus kws kho mob yuav qhia koj kom noj ruxolitinib los ntawm lub raj nasogastric (NG). Koj tus kws kho mob lossis tus kws muag tshuaj yuav piav qhia yuav ua li cas npaj ruxolitinib los ntawm NG raj.
Koj tus kws kho mob yuav xaj kom kuaj ntshav ua ntej thiab thaum koj kho mob kom pom tias koj cuam tshuam li cas los ntawm cov tshuaj no. Koj tus kws kho mob tuaj yeem nce lossis txo koj cov koob tshuaj ruxolitinib thaum koj kho, lossis qhia koj kom tsis txhob noj ruxolitinib ib ntus. Qhov no nyob ntawm seb cov tshuaj ua haujlwm zoo li cas rau koj, koj qhov kev kuaj sim, thiab yog tias koj muaj kev phiv. Tham nrog koj tus kws kho mob txog koj li cas thaum koj kho. Txuas ntxiv mus noj ruxolitinib txawm tias koj hnov zoo. Tsis txhob noj ruxolitinib yam tsis tau tham nrog koj tus kws kho mob. Yog tias koj tus kws kho mob txiav txim siab tso tseg koj txoj kev kho mob nrog ruxolitinib, koj tus kws kho mob yuav txo koj cov tshuaj maj mam.
Nug koj tus kws muag tshuaj lossis tus kws kho mob kom luam ib daim qauv ntawm cov chaw tsim khoom cov ntaub ntawv rau tus neeg mob.

Daim ntawv thov ntawm Ruxolitinib CAS 941678-49-5

Ruxolitinib, nrog CAS tus lej 941678-49-5, yog cov tshuaj uas feem ntau siv los kho qee yam ntshav tsis txaus thiab mob o. Nov yog qee qhov kev siv ntawm Ruxolitinib:

Myelofibrosis:Ruxolitinib tau pom zoo rau kev kho mob ntawm myelofibrosis, ib qho tsis tshua muaj pob txha pob txha mob uas tshwm sim los ntawm kev tsim cov qe ntshav tsis zoo thiab kev loj hlob ntawm fibrous caws pliav hauv pob txha pob txha. Nws pab txo cov tsos mob xws li mob poov xab, qaug zog, thiab tawm hws hmo ntuj, thiab tuaj yeem txhim kho tag nrho lub neej zoo rau cov neeg mob myelofibrosis.

Polycythemia Vera:Ruxolitinib kuj tseem siv rau hauv kev kho mob ntawm polycythemia vera, mob qog noj ntshav ntev uas tshwm sim los ntawm kev tsim cov qe ntshav liab ntau dhau. Nws pab tswj tus kab mob los ntawm kev txo qhov xav tau ntawm phlebotomy (bloodletting) thiab tswj cov tsos mob cuam tshuam nrog tus po loj.

Graft-versus-Host Disease (GVHD):Ruxolitinib qee zaum siv rau kev kho mob ntawm cov kab mob graft-tiv thaiv-tus tswv tsev, ib qho teeb meem uas tuaj yeem tshwm sim tom qab hloov qia cell. Nws pab txo qhov mob thiab cov tsos mob cuam tshuam nrog GVHD, xws li daim tawv nqaij ua pob khaus, teeb meem plab hnyuv, thiab teeb meem daim siab.

Rheumatoid mob caj dab:Ruxolitinib tau pom muaj peev xwm hauv kev kho mob rheumatoid mob caj dab, kab mob autoimmune uas ua rau mob pob qij txha thiab kev puas tsuaj. Nws raug soj ntsuam raws li kev xaiv kho mob rau cov neeg mob uas tsis tau teb zoo rau lwm cov tshuaj.

Alopecia Areata:Ruxolitinib kuj tau pom cov lus cog tseg hauv kev kho mob ntawm alopecia areata, ib qho mob autoimmune uas ua rau cov plaub hau poob. Nws yog feem ntau siv topically raws li ib tug cream los yog gel formulation los txhawb cov plaub hau regrowth nyob rau hauv cov cheeb tsam cuam tshuam.

Mechanism ntawm kev ua ntawm Ruxolitinib

Ruxolitinib kuj feem ntau muaj kev nyab xeeb thiab zam tau zoo thiab muab cov txiaj ntsig txo qis hauv splenomegaly thiab cov tsos mob hauv cov neeg mob uas rov pib dua ruxolitinib tom qab kev cuam tshuam kev kho mob. Raws li ruxolitinib's mechanism ntawm kev txiav txim, hematologic adverse tshwm sim yog thawj qhov ua rau muaj kev cuam tshuam kev kho mob. Hauv 207 tus neeg mob uas rov pib kho dua tom qab kev kho mob cuam tshuam, ruxolitinib muab txo qis hauv palpable spleen ntev thiab cov tsos mob ua ntej thiab tom qab kev cuam tshuam kev kho mob. Tom qab rov pib kho, cov neeg mob tuaj yeem nyob twj ywm ntawm ruxolitinib ntawm qhov nruab nrab ntawm ≈10 mg kev twv, thiab cov neeg mob feem ntau tsis xav tau lwm qhov cuam tshuam. Tus nqi ntawm cov xwm txheej tsis zoo tsis tau nce ntxiv tom qab rov pib kho. Tsis tas li ntawd, tus nqi txiav tawm tom qab rov pib kho dua yog piv rau qhov pom hauv cov neeg kawm tag nrho. Nco ntsoov, tsis muaj pov thawj ntawm kev tshem tawm tom qab txiav tawm ntawm kev kho mob ruxolitinib hauv pawg neeg mob no.
Cov xwm txheej tsis zoo ntawm ruxolitinib hauv cov neeg mob uas muaj kev pheej hmoo nruab nrab tau ua raws li qhov uas tau tshaj tawm yav dhau los hauv cov neeg mob uas muaj kev pheej hmoo siab dua. Tus nqi ntawm cov xwm txheej tsis zoo hematologic tau zoo sib xws hauv ob pawg ntawm cov neeg mob, txawm hais tias cov neeg uas muaj kev pheej hmoo siab dua MF tau tshaj tawm txog kev qaug zog ntau dua (12.9% piv rau 5.5%). Herpes zoster reactivation tau pom nyob rau hauv ob pawg, nrog rau cov neeg mob nruab nrab-kev pheej hmoo tshaj tawm cov nqi ntau dua (8.0% piv rau 3.6%).
Cov neeg mob uas muaj qhov nruab nrab -1-kev pheej hmoo MF tau ua tiav qhov kev txo qis hauv qhov loj ntawm tus po thiab cov tsos mob txhim kho zoo ib yam nrog cov pom hauv nruab nrab -2- thiab cov neeg mob uas muaj kev pheej hmoo siab rau hauv txoj kev tshawb no. Nyob rau lub lim tiam 24, me ntsis ntxiv cov neeg mob nrog nruab nrab-- kev pheej hmoo MF tau ua tiav ntau dua lossis sib npaug li 50% txo los ntawm cov hauv paus hauv palpable spleen ntev dua li cov neeg mob hauv tag nrho cov pej xeem (63.8% piv rau 56.9%, feem); cov nqi tau zoo sib xws ntawm lub lim tiam 48 (60.5% piv rau 62.3%). Tsis tas li ntawd, qhov zoo sib xws ntawm cov neeg mob hauv txhua pawg tau ua tiav ntau dua lossis sib npaug li 50% txo los ntawm cov hauv paus hauv palpable spleen ntev txhua lub sijhawm (tag nrho cov pej xeem, 69%; nruab nrab-1- cov neeg mob pheej hmoo, 77.6%). Lub sij hawm nruab nrab rau cov lus teb spleen kuj zoo ib yam (4.7 piv rau 5.1 lub lis piam). Ib yam li ntawd, qhov kev faib ua feem ntawm cov neeg mob uas ua tiav cov txiaj ntsig kev kho mob hauv cov tsos mob (≈ 30% txog 40%) yog nyob rau hauv qhov kev xav tau thiab ua raws li qhov pom ntawm tag nrho cov neeg JUMP (≈45% txog 50%).

Peb lub Hoobkas

Zhejiang Fengfu Pharma Co., txwv tsis pub koom nrog hauv kev txhim kho, tsim khoom thiab kev lag luam ntawm cov khoom siv tshuaj, cov khoom xyaw zaub mov, cov vitamins, cov tshuaj nruab nrab thiab tshuaj.
Fengfu Pharma, headquartered nyob rau hauv Hangzhou, Tuam Tshoj, nrog 3 ntau lawm bases nyob rau hauv Shandong, Zhejiang thiab Hebei nyias, uas muaj ntau xyoo ntawm kev paub nyob rau hauv zus tau tej cov APIs, vitamins thiab tshuaj cov khoom. Cov chaw no tau lees paub GMP, ISO, FAMI-QS, KOSHER, HALAL, thiab lwm yam. Peb muaj kev tswj xyuas tag nrho peb cov khoom tsim, tsim, thiab tsim cov txheej txheem, ua tsaug rau peb cov cuab yeej siv siab heev, cov txheej txheem, thiab cov chaw soj ntsuam.
Nrog rau kev muaj peev xwm tseem ceeb hauv kev siv tshuaj thiab zaub mov noj qab haus huv, Fengfu Pharma tau tsim kev lag luam thoob plaws ntiaj teb. Peb muaj Strategic Marketing Partners feem hauv Mumbai thiab Dubai. Peb npaj txhij los muab koj nrog peb cov khoom thiab cov kev pabcuam zoo tshaj plaws.
Peb lub hom phiaj yog los muab koj cov khoom lag luam zoo thiab cov kev pabcuam tshaj lij rau kev sib nrig sib pab. Peb kuj txaus siab ua haujlwm nrog cov neeg koom tes thoob ntiaj teb los tsim kom muaj lub neej yav tom ntej zoo ua ke.

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FAQ

Q: Cov tshuaj ruxolitinib CAS 941678-49-5 siv rau dab tsi?

A: Ruxolitinib CAS 941678-49-5 yog cov tshuaj siv los tswj thiab kho myelofibrosis, polycythemia vera, thiab steroid-refractory acute graft-tiv thaiv-tus kab mob. Nws yog nyob rau hauv Janus Kinase inhibitor chav kawm ntawm cov tshuaj.

Q: Puas yog ruxolitinib CAS 941678-49-5 yog kws khomob?

A: Ruxolitinib CAS 941678-49-5 tsis yog kws khomob. Nws yog ib hom kev kho mob uas ua haujlwm los pab tswj kev tsim cov qe ntshav. Tshawb nrhiav dab tsi tuaj yeem ua tau nrog ruxolitinib CAS 941678-49-5 rau kev kho mob polycythemia vera hauv cov neeg mob uas tsis tau txais txiaj ntsig los ntawm HU.

Q: Dab tsi yog kev kho mob siv ruxolitinib CAS 941678-49-5?

A: Ruxolitinib CAS 941678-49-5 phosphate tuaj yeem nres kev loj hlob ntawm cov qog nqaij hlav cancer los ntawm kev thaiv qee cov enzymes uas xav tau rau kev loj hlob ntawm tes. Cov tshuaj siv tshuaj khomob, xws li azacytidine, ua haujlwm sib txawv los tiv thaiv kev loj hlob ntawm cov qog nqaij hlav cancer, los ntawm kev tua cov hlwb, los ntawm kev txwv tsis pub faib, lossis txwv tsis pub lawv kis.

Q: Dab tsi yog qhov txaus ntshai ntawm ruxolitinib CAS 941678-49-5?

A: Ruxolitinib CAS 941678-49-5 kuj tuaj yeem ua rau los ntshav los ntawm txhua qhov hauv koj lub cev. Cov tsos mob ntawm los ntshav los ntawm lwm qhov hauv lub cev muaj xws li cov ntshav hauv koj cov zis los yog poo (cov quav), quav dub, ntuav lossis hnoos ntshav, mob taub hau, kiv taub hau lossis tsis muaj zog. Hu rau koj tus kws kho mob lossis tus kws saib xyuas neeg mob tam sim ntawd yog tias koj muaj cov tsos mob los ntshav.

Q: Puas yog ruxolitinib CAS 941678-49-5 kim?

A: Ruxolitinib CAS 941678-49-5 yog ib tug tswv cuab ntawm cov tshuaj multikinase inhibitors thiab feem ntau yog siv rau Graft-tiv thaiv-tus kab mob, Myelofibrosis, Myeloproliferative Disorders, thiab lwm yam.

Q: Puas yog ruxolitinib CAS 941678-49-5 regrow plaub hau?

A: Hauv ib txoj kev tshawb fawb uas muaj 66 tus neeg mob, kwv yees li ib feem peb muaj ntau dua 50% tawv taub hau regrowth tom qab tau kho nrog cov kab mob JAK inhibitor rau 3 lub hlis. Hauv lwm qhov kev sim, cuaj ntawm 12 tus neeg mob noj ruxolitinib CAS 941678-49-5 tau ntsib cov plaub hau ua tiav hauv 6 lub hlis.

Q: Puas yog ruxolitinib CAS 941678-49-5 txhim kho txoj sia?

A: Qhov kev tshawb fawb sib koom ua ke ntawm cov kev sim no tau pom tias kev kho mob mus sij hawm ntev nrog ruxolitinib CAS 941678-49-5 ntev ciaj sia taus piv nrog cov kev kho mob zoo tshaj plaws los yog cov placebo hauv cov neeg mob uas muaj int -2 lossis MF muaj kev pheej hmoo siab.

Q: Koj tuaj yeem noj ruxolitinib CAS 941678-49-5 ntev npaum li cas?

A: Koj yuav tsum tau noj ruxolitinib txuas ntxiv mus ntev npaum li koj tus kws kho mob qhia rau koj. Qhov no yog kev kho mob mus ntev. Koj tus kws kho mob yuav niaj hnub saib xyuas koj tus mob kom paub tseeb tias qhov kev kho mob muaj qhov xav tau. Yog tias koj muaj lus nug txog yuav siv sijhawm ntev npaum li cas Jakavi, tham nrog koj tus kws kho mob lossis tus kws muag tshuaj.

Q: Cov txiaj ntsig ntawm ruxolitinib CAS 941678-49-5 yog dab tsi?

A: Ruxolitinib CAS 941678-49-5 blocks (inhibits) cov cim los ntawm cov noob tsis raug. Qhov no txo cov qe ntshav ntxiv. Feem ntau koj yuav tau kuaj ntshav txhawm rau kuaj qhov tsis zoo JAK1 lossis JAK2 noob ua ntej koj tau kho nrog ruxolitinib CAS 941678-49-5. ruxolitinib CAS 941678-49-5 kuj tseem tuaj yeem thaiv lwm cov cim qhia uas ua rau cov qe ntshav ntau dhau lawm.

Q: Vim li cas ruxolitinib CAS 941678-49-5 ua rau hnyav nce?

A: Ruxolitinib CAS 941678-49-5 tuaj yeem ua rau qhov hnyav nce los ntawm kev thaiv leptin signaling hauv hlwb ntawm JAK2/STAT3. Ntshav.

Q: ruxolitinib CAS 941678-49-5 siv tau li cas?

A: Kev soj ntsuam kev ciaj sia ntawm cov ntaub ntawv sib sau ua ke ntawm qhov kev soj ntsuam nruab nrab ntawm kwv yees li 3 xyoos kwv yees li 35% txo qhov kev pheej hmoo ntawm kev tuag rau cov neeg mob randomized rau ruxolitinib CAS 941678-49-5 piv nrog cov randomized rau cov placebo lossis BAT, nrog baseline splenomegaly raws li ib qho tseem ceeb tsis zoo prognostic.

Q: ruxolitinib CAS 941678-49-5 pom zoo rau dab tsi?

A: Nruab nrab lossis muaj kev pheej hmoo siab myelofibrosis, suav nrog thawj myelofibrosis, post-polycythemia vera myelofibrosis thiab post-tseem ceeb thrombocythemia myelofibrosis hauv cov laus.
polycythemia vera nyob rau hauv cov neeg laus uas tau teb tsis txaus los yog intolerant ntawm hydroxyurea.

Q: Yuav ua li cas yog tias koj tsis noj ruxolitinib CAS 941678-49-5?

A: Ruxolitinib CAS 941678-49-5 discontinuation syndrome (RDS) tshwm sim nyob rau hauv 21 hnub ntawm kev kho mob nres thiab yog tus cwj pwm los ntawm ib tug mob rov qab los ntawm cov tsos mob ntawm tus kab mob, ceev splenomegaly, zuj zus ntawm cytopenias, thiab qee zaus hemodynamic decompensation, nrog rau mob ua pa nyuaj siab syndrome thiab poob siab.

Q: Cov tshuaj twg yog ruxolitinib CAS 941678-49-5?

A: Ruxolitinib CAS 941678-49-5 yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua kinase inhibitors. Nws ua haujlwm los kho myelofibrosis thiab PV los ntawm kev thaiv cov cim qhia uas ua rau cov qog nqaij hlav cancer ntau. Qhov no yuav pab kom tsis txhob kis kab mob qog noj ntshav. Nws ua haujlwm los kho GVHD los ntawm kev thaiv cov cim ntawm lub hlwb uas ua rau GVHD.

Q: Qhov kev vam meej ntawm ruxolitinib CAS 941678-49-5 yog dab tsi?

A: Tus {{0}}, 2-, thiab 3-xyoo ciaj sia nyob rau hauv cov neeg mob uas muaj kev pheej hmoo siab ruxolitinib CAS 941678-49-5- kho cov neeg mob tau zoo tshaj plaws ntawm 95%, 83% , thiab 63% piv nrog 81%, 58%, thiab 35% hauv pawg tswj xyuas keeb kwm (HR=0.50; 95% CI, 0.31-0.81; P=} 006 ib.

Q: Puas yog ruxolitinib CAS 941678-49-5 ua rau hnyav nce?

A: Hauv kev xaus, kev ua haujlwm ntawm lub hom phiaj ntawm ruxolitinib CAS 941678-49-5 tuaj yeem tshem tawm cov teeb meem postprandial leptin thiab ua li ntawd, ua rau hyperphagia thiab ua rau qhov hnyav nce los ntawm cov neeg mob feem ntau.

Q: Dab tsi yog qhov cuam tshuam ntev ntawm ruxolitinib CAS 941678-49-5?

A: Tsis muaj lus nug txog cov tshuaj no ua rau muaj sia nyob ntev. Cov xwm txheej tseem ceeb cuam tshuam nrog ruxolitinib CAS 941678-49-5 yog lub peev xwm rau kev loj hlob ntawm cytopenia, anemia, thiab thrombocytopenia.

Q: ruxolitinib CAS 941678-49-5 ua haujlwm li cas?

A: Ruxolitinib yog ib qho kev xaiv Janus kinase (JAK) inhibitor. Nws ua haujlwm los ntawm kev thaiv kev ua haujlwm ntawm cov enzymes hu ua JAK1 thiab JAK2, uas koom nrog hauv cov xov tooj ntawm tes taw qhia txoj hauv kev cuam tshuam txog kev tiv thaiv kab mob thiab kev tsim cov ntshav. Los ntawm inhibiting cov enzymes, Ruxolitinib pab tswj kev loj hlob ntawm tes tsis zoo thiab txo qhov mob ntawm qee yam kab mob.

Q: Koj puas tuaj yeem haus ruxolitinib CAS 941678-49-5?

A: Txawm hais tias nws muaj kev nyab xeeb rau haus cawv hauv qhov nruab nrab thaum noj ruxolitinib CAS 941678-49-5, peb xav kom koj tsis txhob tshaj qhov txwv txhua lub lim tiam ntawm 14 units ntawm cawv ib lub lis piam rau txiv neej thiab poj niam. Cawv tuaj yeem ua rau lub cev qhuav dej, thiab nws tseem ceeb heev kom tsis txhob ua kom lub cev qhuav dej yog tias koj muaj MPN.

Q: Dab tsi yog qhov kev pheej hmoo ntawm thrombosis nrog ruxolitinib CAS 941678-49-5?

A: Peb kwv yees qhov kev pheej hmoo ntawm thrombosis ntawm 0.56 rau ruxolitinib CAS 941678-49-5 BAT, sib xws rau qhov tshwm sim ntawm 3.09% thiab 5.51% cov neeg mob hauv ib xyoos, feem.

Cim npe nrov: ruxolitinib cas 941678-49-5, Tuam Tshoj ruxolitinib cas 941678-49-5 manufacturers, lwm tus neeg, Hoobkas